ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Language matters: CRE vs. CPE; SDD vs. I; and MDR, XDR, PDR, UDR vs. DTR
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
Mirror Bacteria: An AMR threat of unprecedented magnitude
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
FDA workshop: Insights on inhaled antifungals and antibacterials
De-risking vaccine development: Insights spanning decades of experience
FDA analysis of 40-years of antibacterial development: Dheman et al.
FDA Workshop: Animal models in support of narrow-spectrum agents for A. baumannii and P. aeruginosa
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
NIAID workshop: What is a robust PK-PD package?
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet